While I do always have it on hand, I hardly ever use it, I've found that my family and I get sick less often if we are always exposed to small amounts of stuff from the usual everyday living and nature germs don't bother me at all.
Purell can create stronger bugs also but you need to know your kids and family, if your kid has always come down with every little thing that comes along and it helps to stem the tide of sickness then I'm all for it.
My mom has started using it all the time and now gets sick more often then ever before.