Exercise helps, but only when I've got enough energy to get off the couch ;)
I find that routines help a lot. And cooking - real food always makes life better.
This week is killing me, between last weekend's funeral mess and this weekend's con. Routines are off, we have no nursing while out of town...and so far the food is ok, but we're making sandwiches in our hotel room, which isn't going to work for long.
To some extent, the fact that I *do* work full time helps - there's a mental break that way.
I get caught up on sleep on the weekends usually (routines again), but this weekend isn't looking promising. I was up until 2:30 last night trying to get Alex to sleep, while everyone else slept through it.